par Maxime

TASE

septembre 18, 2013 dans Pro, Projects par Maxime

Project: Transmitted Allele Search Engine
Lab: INSERM: Institut des Neurosciences de Montpellier (INM)
Supervisor: C.P.HAMEL
Link: http://www.transwalkers.com/TASE/

tase-home

Problem: The team I’ve join work on rare hereditary diseases of the eye. Each patient have one unique mutation (two in recessive case), but there is about 200 genes that could cause close diseases. The challenge is to find which gene is mutated for each patient.

Solution: Medical doctors make clinical diagnosis of families and team perform SNP-chips on individuals. I’ve made a software that manage data, perform linkage analyses, and prioritize candidates regions.

More info soon…

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par Maxime

ScripTree

juillet 6, 2009 dans Pro, Projects par Maxime

Project: ScripTree Web Interface
Lab: Laboratoire d’Informatique, de Robotique et de Microélectronique de Montpellier (LIRMM)
Supervisor: F.CHEVENET
Link: http://www.transwalkers.com/scriptree/

Scriptree

Problem: Phylogenetic trees are usefull in history of evolution studies. For computation and manipulation, trees are store in a bracket separated format (newick). In addition of tree conformation, biologists deals with various annotations data and want to visualize it on leafs or eages. The team I’ve join develop a scripting language for automatically stack annotations (graphical or textual) on the tree. Scriptree take 3 text files (tree conformation, annotations and procedures) and output the final figure of the decorated tree. But user need some scripting skills to write the procedures.

Solution: My project was to design a userfirendly web interface for scriptree. This interface is based on graphical buttons and documented list of choices. that help biologists to understand what they can do and how.
I’ve also worked to add some functions in scriptree like node annotations, SVG output format and particular tree conformations.

More info soon…

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